Profile photo of Sean Carroll
Contact Info
Phone: 301.405.1952
Lab: 2229 Bioscience Research Bldg
Alt Email: carrolls@hhmi.org
Sean Carroll
Distinguished University Professor
Andrew and Mary Balo and Nicholas and Susan Simon Endowed Chair
Vice President for Science Education, Howard Hughes Medical Institute

Research Interests 

The origin of novelty is one of the central questions of evolution. We seek to understand, in general, the relative contributions of different mechanisms – gene co-option, gene duplication and loss, regulatory and protein sequence changes – to the evolution of different kinds of traits. Our research has focused on the evolution of morphological traits in animals, and more recently, on biochemical novelties such as the evolution of snake venom. 


Recent Books

  • Carroll, S.B. (2020) A Series of Fortunate Events: Chance and the Making of the Planet, Life, and You. Princeton University Press.

  • Carroll, S.B. (2016) The Serengeti RulesThe quest to discover how life works and why it matters. Princeton University Press.

  • Carroll, S.B. (2013) Brave Genius: A Scientist, a Philosopher, and Their Daring Adventures from the French Resistance to the Nobel Prize. 


All Publications

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Latest Publications via PubMed

Giorgianni MW,Dowell NL,Griffin S,Kassner VA,Selegue JE,Carroll SB
Proc Natl Acad Sci U S A. 2020 May 19;117(20):10911-10920. doi: 10.1073/pnas.1920011117. Epub 2020 May 4
Loehlin DW,Ames JR,Vaccaro K,Carroll SB
Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12383-12389. doi: 10.1073/pnas.1904071116. Epub 2019 May 31
Finet C,Slavik K,Pu J,Carroll SB,Chung H
Genome Biol Evol. 2019 Jun 1;11(6):1541-1551. doi: 10.1093/gbe/evz094. Epub
Dowell NL,Giorgianni MW,Griffin S,Kassner VA,Selegue JE,Sanchez EE,Carroll SB
Curr Biol. 2018 Apr 2;28(7):1016-1026.e4. doi: 10.1016/j.cub.2018.02.031. Epub 2018 Mar 22
Dowell NL,Giorgianni MW,Kassner VA,Selegue JE,Sanchez EE,Carroll SB
Curr Biol. 2016 Sep 26;26(18):2434-2445. doi: 10.1016/j.cub.2016.07.038. Epub 2016 Sep 15
Loehlin DW,Carroll SB
Proc Natl Acad Sci U S A. 2016 May 24;113(21):5988-92. doi: 10.1073/pnas.1605886113. Epub 2016 May 9
Chung H,Carroll SB
Bioessays. 2015 Jul;37(7):822-30. doi: 10.1002/bies.201500014. Epub 2015 May 19
Koshikawa S,Giorgianni MW,Vaccaro K,Kassner VA,Yoder JH,Werner T,Carroll SB
Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7524-9. doi: 10.1073/pnas.1509022112. Epub 2015 Jun 1