Dr. Jeff Maltas
Contact Info
Jeff Maltas
Assistant Professor

Start Date

July, 2026


Research Interests

My group uses a combination of theoretical and experimental approaches to study the short-term eco-evolutionary dynamics that emerge in large, rapidly evolving populations such as bacteria, yeast, and cancer. We leverage recent technological advances that have revolutionized our ability to study complex, evolving systems with unprecedented resolution.

Work from multiple disciplines – including ecology, statistical physics, and economics – reveals that complex systems are often dominated by emergent behavior not easily recognizable from the behavior of the constituent parts. In a similar spirit, using tools from population genetics, game theory, and statistical physics, we aim to understand how evolution at the population-level emerges from its constituent parts: competition/cooperation between lineages, population density, spatial heterogeneity, and fluctuating environments.

Critically, many of the most challenging public health concerns worldwide are the result of evolving diseases such as cancer, COVID-19, and antibiotic resistance. As such it is imperative to translate our understanding of these fundamental processes into a testable theoretical framework to help us better forecast, and ultimately control, the evolution of these systems.

Latest Publications via PubMed

Card KJ,Crozier D,Durmaz A,Gray J,Creary J,Stocks A,Maltas J,Bonomo RA,Burke ZDC,Scott JG
Proc Natl Acad Sci U S A. 2025 Sep 30;122(39):e2507962122. doi: 10.1073/pnas.2507962122. Epub 2025 Sep 25
Barker-Clarke RJ,Gray JM,Leither S,Strobl MAR,Maltas J,Tadele DS,Hinczewski M,Scott JG
Res Sq. 2025 Sep 8;:. pii: rs.3.rs-7403028. doi: 10.21203/rs.3.rs-7403028/v1. Epub 2025 Sep 8
Barker-Clarke RJ,Gray JM,Leither S,Strobl MAR,Maltas J,Tadele DS,Hinczewski M,Scott JG
bioRxiv. 2025 Aug 25;:. pii: 2023.03.15.532871. doi: 10.1101/2023.03.15.532871. Epub 2025 Aug 25
King ES,Stacy AE,Weaver DT,Maltas J,Barker-Clarke R,Dolson E,Scott JG
Sci Adv. 2025 Jun 13;11(24):eadv1268. doi: 10.1126/sciadv.adv1268. Epub 2025 Jun 11
Card KJ,Crozier D,Durmaz A,Gray J,Creary J,Stocks A,Maltas J,Bonomo RA,Burke ZDC,Scott JG
bioRxiv. 2025 Apr 5;:. pii: 2023.11.30.569373. doi: 10.1101/2023.11.30.569373. Epub 2025 Apr 5
Khalil A,Dinh T,Parks M,Obeng RC,Gryder B,Kresak A,Wang Y,Maltas J,Bedrock M,Wei X,Faber Z,Rahm M,Scott J,LaFramboise T,Wang Z,McFarland C
bioRxiv. 2025 Mar 17;:. pii: 2025.03.15.642187. doi: 10.1101/2025.03.15.642187. Epub 2025 Mar 17
Maltas J,Huynh A,Wood KB
PLoS Biol. 2025 Jan;23(1):e3002970. doi: 10.1371/journal.pbio.3002970. Epub 2025 Jan 8
Weaver DT,King ES,Maltas J,Scott JG
Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2303165121. doi: 10.1073/pnas.2303165121. Epub 2024 Apr 12
Maltas J,Tadele DS,Durmaz A,McFarland CD,Hinczewski M,Scott JG
PRX Life. 2024 Apr-Jun;2(2):. pii: 023010. doi: 10.1103/prxlife.2.023010. Epub 2024 Jun 3
Maltas J,Tadele DS,Durmaz A,McFarland CD,Hinczewski M,Scott JG
bioRxiv. 2024 Mar 11;:. pii: 2023.03.16.533001. doi: 10.1101/2023.03.16.533001. Epub 2024 Mar 11
Maltas J,Killarney ST,Singleton KR,Strobl MAR,Washart R,Wood KC,Wood KB
Nat Ecol Evol. 2024 Jan;8(1):176. doi: 10.1038/s41559-023-02300-9. Epub
Maltas J,Killarney ST,Singleton KR,Strobl MAR,Washart R,Wood KC,Wood KB
Nat Ecol Evol. 2024 Jan;8(1):147-162. doi: 10.1038/s41559-023-02255-x. Epub 2023 Nov 27
Weaver DT,King ES,Maltas J,Scott JG
bioRxiv. 2023 Nov 16;:. pii: 2023.01.12.523765. doi: 10.1101/2023.01.12.523765. Epub 2023 Nov 16
Farrokhian N,Maltas J,Dinh M,Durmaz A,Ellsworth P,Hitomi M,McClure E,Marusyk A,Kaznatcheev A,Scott JG
Sci Adv. 2022 Jul;8(26):eabm7212. doi: 10.1126/sciadv.abm7212. Epub 2022 Jul 1
Weaver DT,McElvany BD,Gopalakrishnan V,Card KJ,Crozier D,Dhawan A,Dinh MN,Dolson E,Farrokhian N,Hitomi M,Ho E,Jagdish T,King ES,Cadnum JL,Donskey CJ,Krishnan N,Kuzmin G,Li J,Maltas J,Mo J,Pelesko J,Scarborough JA,Sedor G,Tian E,An GC,Diehl SA,Scott JG
PLoS One. 2021;16(7):e0241734. doi: 10.1371/journal.pone.0241734. Epub 2021 Jul 26
Maltas J,McNally DM,Wood KB
Evolution. 2021 Jan;75(1):10-24. doi: 10.1111/evo.14121. Epub 2020 Dec 13
Maltas J,Krasnick B,Wood KB
Mol Biol Evol. 2020 May 1;37(5):1394-1406. doi: 10.1093/molbev/msz303. Epub
Dean Z,Maltas J,Wood KB
PLoS Pathog. 2020 Mar;16(3):e1008278. doi: 10.1371/journal.ppat.1008278. Epub 2020 Mar 2
Maltas J,Wood KB
PLoS Biol. 2019 Oct;17(10):e3000515. doi: 10.1371/journal.pbio.3000515. Epub 2019 Oct 25
Maltas J,Palo D,Wong CK,Stefan S,O'Connor J,Al Aayedi N,Gaire M,Kinn D,Urayama P
RSC Adv. 2018 Dec 7;8(72):41526-41535. doi: 10.1039/c8ra07691j. Epub 2018 Dec 12