Quentin Gaudry
Assistant Professor
Contact
Email: qgaudry@umd.edu
Office Phone:301.405.9451
Lab:
Fax: (301) 314-9358
Office Address: 1108 Bioscience Research Building
Lab URL: http://gaudrylab.weebly.com/
Teaching
Graduate Program Affiliations
Research Interests
We are interested in how nervous systems generate complex behaviors and give rise to sensory perceptions. We study these questions in the fly, Drosophila, selected for its rich history as a model system in neurobiology, and its powerful genetic toolbox. Our principal approach is to use whole-cell patch-clamp electrophysiology to record from identified neurons in neural circuits involved in courtship behavior or aggression. We can then alter the properties of these cells using the GAL4/UAS system of the fly to determine how the neurons function in the circuit. We are also developing mathematical models and highly quantitative behavioral assays to determine how such circuits ultimately shape behavioral output. These methods allow us to ask questions central to neurobiology, such as:
Select Publications
Gaudry Q, Hong EJ, Kain J, de Bivort B, Wilson RI. Asymmetric neurotransmitter release at primary afferent synapses enables rapid odor localization in Drosophila. 2013 Nature 493:424-428.
Lehnert BP, Baker AE, Gaudry Q, Chiang AS, and Wilson RI. Distinct roles of TRP channels in auditory transduction and amplification in Drosophila. 2013 Neuron 77:115-128.
Gaudry Q, Kristan WB Jr. Decision Points: The factors influencing the decision to feed in the medicinal leech. Frontiers in Neuroscience. 2012; 6.
Gaudry Q, Nagel K, Wilson RI. Smelling on the fly: sensory cues and strategies for olfactory navigation in Drosophila. Current Opinion in Neurobiology. 2012; 22:216-222.
Gaudry Q, Kristan WB Jr. Feeding mediated distention inhibits swimming in the medicinal leech. Journal of Neuroscience. 2010; 30:9753-9761.
Gaudry Q, Ruiz N, Huang T+, Kristan WB III, Kristan WB Jr. Behavioral choice across leech species: chacun à son gout. Journal of Experimental Biology. 2010; 213:1356-1365
Gaudry Q, Kristan WB Jr. Behavioral choice by presynaptic inhibition of tactile sensory terminals. Nature Neuroscience 2009; 12:1450-1457.
Education
• Postdoc, Harvard Medical School, 2012
• Ph.D., Neuroscience, UC San Diego, 2008
• B.S., Emory University, 2002
Contact
Email: qgaudry@umd.edu
Office Phone:301.405.9451
Lab:
Fax: (301) 314-9358
Office Address: 1108 Bioscience Research Building
Lab URL: http://gaudrylab.weebly.com/
Teaching
Graduate Program Affiliations
Research Interests
We are interested in how nervous systems generate complex behaviors and give rise to sensory perceptions. We study these questions in the fly, Drosophila, selected for its rich history as a model system in neurobiology, and its powerful genetic toolbox. Our principal approach is to use whole-cell patch-clamp electrophysiology to record from identified neurons in neural circuits involved in courtship behavior or aggression. We can then alter the properties of these cells using the GAL4/UAS system of the fly to determine how the neurons function in the circuit. We are also developing mathematical models and highly quantitative behavioral assays to determine how such circuits ultimately shape behavioral output. These methods allow us to ask questions central to neurobiology, such as:
- How do neurons encode stimuli and social cues that pertain to courtship behavior and aggression?
- How do circuits integrate multi-modal sensory stimuli to choose an appropriate behavioral output?
- Do individual neurons tend to be involved in the generation of multiple behaviors? Are they multifunctional?
- How do sensory systems and neuromodulatory circuits interact to govern behavioral output?
- How do brief and transient sensory stimuli lead to long-lasting behavioral output?
Select Publications
Gaudry Q, Hong EJ, Kain J, de Bivort B, Wilson RI. Asymmetric neurotransmitter release at primary afferent synapses enables rapid odor localization in Drosophila. 2013 Nature 493:424-428.
Lehnert BP, Baker AE, Gaudry Q, Chiang AS, and Wilson RI. Distinct roles of TRP channels in auditory transduction and amplification in Drosophila. 2013 Neuron 77:115-128.
Gaudry Q, Kristan WB Jr. Decision Points: The factors influencing the decision to feed in the medicinal leech. Frontiers in Neuroscience. 2012; 6.
Gaudry Q, Nagel K, Wilson RI. Smelling on the fly: sensory cues and strategies for olfactory navigation in Drosophila. Current Opinion in Neurobiology. 2012; 22:216-222.
Gaudry Q, Kristan WB Jr. Feeding mediated distention inhibits swimming in the medicinal leech. Journal of Neuroscience. 2010; 30:9753-9761.
Gaudry Q, Ruiz N, Huang T+, Kristan WB III, Kristan WB Jr. Behavioral choice across leech species: chacun à son gout. Journal of Experimental Biology. 2010; 213:1356-1365
Gaudry Q, Kristan WB Jr. Behavioral choice by presynaptic inhibition of tactile sensory terminals. Nature Neuroscience 2009; 12:1450-1457.
Education
• Postdoc, Harvard Medical School, 2012
• Ph.D., Neuroscience, UC San Diego, 2008
• B.S., Emory University, 2002
